Product Info Summary
SKU: | M00193-1 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human |
Host: | Mouse |
Application: | Flow Cytometry, IHC-P, IHC-F, WB |
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Product info
Product Name
Anti-Hu CD38 Purified Monoclonal Antibody
SKU/Catalog Number
M00193-1
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Hu CD38 Purified Monoclonal Antibody (Catalog# M00193-1). Tested in Flow Cytometry, WB, IHC-P, IHC-F application(s). This antibody reacts with Human.
Storage & Handling
Store at 2-8°C. Do not freeze.
Cite This Product
Anti-Hu CD38 Purified Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00193-1)
Host
Mouse
Contents
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Clonality
Monoclonal
Clone Number
HIT2
Isotype
Mouse IgG1
Immunogen
Human thymocytes in foetus. The mouse monoclonal antibody HIT2 reacts with an extracellular epitope of CD38, a 45 kDa type II transmembrane glycoprotein strongly expressed mainly on plasma cells and activated T and B lymphocytes; it is an antigenic marker of lymphoid cells. Its binding is blocked by daratumumab.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M00193-1 is reactive to CD38 in Human
Applications
M00193-1 is guaranteed for Flow Cytometry, IHC-P, IHC-F, WB Boster Guarantee
Observed Molecular Weight
42 kDa
Calculated molecular weight
34.328kDa
Background of CD38
CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induce activation, proliferation and differentiation of mature lymphocytes and mediate apoptosis of myeloid and lymphoid progenitor cells. Another role of CD38 is provided by enzymatic activity of its extracellular part. CD38 acts as NAD+ glycohydrolase converting NAD+ into ADP-ribose, as ADP-ribosyl cyclase producing cADPR and as cADPR hydrolase, thus affecting levels of calcium-mobilizing metabolites. ADPR produced by CD38 serves as an important second messenger of neutrophil and dendritic cell migration.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Immunohistochemistry (paraffin sections): 10 μg/ml.
Western blotting: 2 μg/ml; positive control: RAJI human cell line, non-reducing conditions.
Flow cytometry: 1-4 µg/ml
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For CD38 (Source: Uniprot.org, NCBI)
Gene Name
CD38
Full Name
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
Weight
34.328kDa
Superfamily
ADP-ribosyl cyclase family
Alternative Names
ADP-ribosyl cyclase 1; ADP-ribosyl Cyclase; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase; cADPr hydrolase 1; CD38 antigen (p45); CD38 antigen; CD38 molecule; CD38; Cyclic ADP-ribose hydrolase 1; Cyclic ADP-ribose Hydrolase; EC 3.2.2.5; NAD(+) nucleosidase; T10 CD38 ADPRC 1, ADPRC1 CD38 molecule ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1|2-phospho-ADP-ribosyl cyclase|2-phospho-cyclic-ADP-ribose transferase|ADP-ribosyl cyclase 1|CD38 antigen (p45)|NAD(+) nucleosidase|cluster of differentiation 38|cyclic ADP-ribose hydrolase 1|ecto-nicotinamide adenine dinucleotide glycohydrolase
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CD38, check out the CD38 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CD38: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Hu CD38 Purified Monoclonal Antibody (M00193-1)
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No publications found for M00193-1
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